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Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Saturday Pap Smear Clinic: addressing barriers to cervical cancer screening
CONCLUSIONS: The availability of Saturday appointments for cervical cancer screening completion can enhance cervical cancer screening compliance among eligible women. Eliminating barriers for women can improve health outcomes.PMID:37451801 | DOI:10.1136/bmjoq-2023-002252
Source: Cancer Control - July 14, 2023 Category: Cancer & Oncology Authors: Brittany Strelow Mollie Francis Gabrielle Gertner Rachel Olson Kholood Abuhadid Deqa Abdi Jordan Anderson Nicole Fellows Stephanie Fink Joy Stevens Sonya Peters Anne Stolp Johanna Tweedy Danielle O'Laughlin Source Type: research
Multimodeling approach to evaluating the efficacy of layering pharmaceutical and nonpharmaceutical interventions for influenza pandemics
Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2300590120. doi: 10.1073/pnas.2300590120. Epub 2023 Jul 3.ABSTRACTWhen an influenza pandemic emerges, temporary school closures and antiviral treatment may slow virus spread, reduce the overall disease burden, and provide time for vaccine development, distribution, and administration while keeping a larger portion of the general population infection free. The impact of such measures will depend on the transmissibility and severity of the virus and the timing and extent of their implementation. To provide robust assessments of layered pandemic intervention strategies, the Cente...
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Pragati V Prasad Molly K Steele Carrie Reed Lauren Ancel Meyers Zhanwei Du Remy Pasco Jorge A Alfaro-Murillo Bryan Lewis Srinivasan Venkatramanan James Schlitt Jiangzhuo Chen Mark Orr Mandy L Wilson Stephen Eubank Lijing Wang Matteo Chinazzi Ana Pastore Y Source Type: research
Human Papillomavirus Inpatient Postpartum Vaccination: Clinical Guideline Implementation
CONCLUSION: Non-Hispanic White, Spanish-speaking, and married patients were disproportionally undervaccinated in our baseline population, but about one quarter of vaccine-eligible patients received 9vHPV vaccination postpartum. Inpatient postpartum 9vHPV vaccination may help narrow disparities in vaccination.PMID:37348091 | DOI:10.1097/AOG.0000000000005220
Source: Obstetrics and Gynecology - June 22, 2023 Category: OBGYN Authors: Ellen C Murphy Stephanie Alimena Andrea Pelletier Nicole Sczekan Nicole A Smith Julianna Schantz-Dunn Khady Diouf Sarah Feldman Source Type: research
